Three journalists, the most recent update on BBC News states five, including cameraman Hussam al-Masri who worked for Reuters, were killed in the strikes, according to officials.
Photographer Mohammed Salama who worked for Al Jazeera, was also killed, the news network confirmed.
Photographer Hatem Khaled, also contracted by Reuters, was injured.
A rescue workers was also among those killed, health officials added.
The victims on the fourth floor of Nasser Hospital were killed in a double-tap strike with one missile hitting first, then another moments later as rescue crews arrived.
Khaled Al Serr, a Palestinian surgeon who works at the hospital, told The Independent that the bombing hit “the main building, the surgical building.
“The civil defence forces and also the paramedics rushed to the area of the bombing to evacuate the injured,” he added. “During the evacuation, we were standing in front of the building looking to work by starting to receive cases to the emergency department from the bombing.
“We were surprised by another bombing to the same spot.”
A live video feed from the hospital by Reuters, operatid by al-Mastri, suddenly shut down at the moment of the initial strike.
Nasser Hospital, based in Khan Younis is the largest in southern Gaza. It has withstood raids and bombardment throughout 22 months of war, with officials citing critical shortages of supplies and staff.
The Israeli military and Prime Minister’s Office both had no immediate comment regarding the strikes.
The latest strike comes weeks after the world expressed shock as six journalists, including prominent Al Jazeera correspondent Anas Al Sharif, were killed in an airstrike.
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